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Clinical trials for Chronic Pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,150 result(s) found for: Chronic Pain. Displaying page 1 of 58.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2015-002972-26 Sponsor Protocol Number: LDN_7323 Start Date*: 2015-12-14
    Sponsor Name:Smerteklinikken
    Full Title: Low dose naltrexone for treatment of pain in patients with fibromyalgia - effect via central mechanism? A randomized, double-blinded, placebo-controlled, cross-over study
    Medical condition: Pain in patients with fibromylagia
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-001258-27 Sponsor Protocol Number: 7612 Start Date*: 2011-06-07
    Sponsor Name:Mads Werner
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    13.1 10018065 - General disorders and administration site conditions 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-003259-20 Sponsor Protocol Number: VenlaTrama_1.0 Start Date*: 2011-09-08
    Sponsor Name:University of Turku
    Full Title: Effect of duloxetine and venlafaxine on the pharmacokinetics and pharmacodynamics of oral tramadol: A three-phase randomized balanced cross-over study in healthy volunteers
    Medical condition: Acute postoperative pain and chronic pain syndromes
    Disease: Version SOC Term Classification Code Term Level
    14.0 10018065 - General disorders and administration site conditions 10066714 Acute pain LLT
    14.0 10018065 - General disorders and administration site conditions 10049475 Chronic pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004804-21 Sponsor Protocol Number: ANST_PREVENT Start Date*: 2020-01-13
    Sponsor Name:Leiden University Medical Center
    Full Title: A Randomized, Double-blind, Placebo-controlled Trial on the Prevention of Chronic Postoperative Pain after Inguinal Hernia and Knee Surgery by Postoperative Treatment with Tapentadol.
    Medical condition: Chronic pain after inguinal hernia surgery and knee replacement surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018920-21 Sponsor Protocol Number: ZICBOL2010 Start Date*: 2011-03-23
    Sponsor Name:Landstinget i Östergötland
    Full Title: Evaluation of a Structured Algorithm for Intrathecal Bolus Doses of Ziconotide(Prialt®) - The Swedish Ziconotide Bolus Study
    Medical condition: Chronic pain
    Disease: Version SOC Term Classification Code Term Level
    12.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-004048-50 Sponsor Protocol Number: 3-062-18 Start Date*: 2019-02-14
    Sponsor Name:University of Aberdeen [...]
    1. University of Aberdeen
    2. NHS Grampian
    Full Title: Double blind randomised controlled trial of exogenous administration of melatonin in chronic pain (DREAM-CP)
    Medical condition: Sleep disturbance in patients with chronic pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004873 10040995 Sleep disturbance LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-023175-26 Sponsor Protocol Number: P_TPT_2010 Start Date*: 2011-01-14
    Sponsor Name:Leiden University Medical Center
    Full Title: Influence of Tapentadol on endogenous modulation of pain in chronic neuropathic pain patients and healthy volunteers
    Medical condition: Chronic pain patients/ mhealthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    12.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002286-40 Sponsor Protocol Number: 1-1 Start Date*: 2006-12-05
    Sponsor Name:Pfizer bv
    Full Title: Chronic Pain Management after Herniorraphy Pregabaline versus Placebo
    Medical condition: Patients suffering from chronic pain of neuropathic character after open hernia repair.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000170-30 Sponsor Protocol Number: MULTIPAIN-2-3-2013 Start Date*: 2013-04-19
    Sponsor Name:Mech-Sense, Aalborg University Hospital
    Full Title: Effects of oxycodon and venlafaxine on human pain processing. A randomized, double-blinded, placebo-controlled, cross-over study
    Medical condition: Healthy volunteers - pain
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-002565-39 Sponsor Protocol Number: 2006015 Start Date*: 2006-11-27
    Sponsor Name:South Tees Acute Hospitals NHS Trust
    Full Title: Effects of the Modification of the Daily Flow Rate with a Constant Daily Dose on Patient's Reported Analgesia in Intathecal Therapy
    Medical condition: Chronic Pain.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-002292-27 Sponsor Protocol Number: NonOnco2008 Start Date*: 2008-06-23
    Sponsor Name:OSPEDALE POLICLINICO S. MATTEO
    Full Title: Long term opioid administration in no-oncologic chronic pain: open label, prospective study on efficacy, safety and pharmacokinetic factors
    Medical condition: chronic pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-001540-22 Sponsor Protocol Number: 76122012 Start Date*: 2012-06-27
    Sponsor Name:Mads Werner
    Full Title: CAPSAICIN PATCH 8% FOR THE TREATMENT OF PERSISTENT PAIN AFTER INGUINAL HERNIOTOMY
    Medical condition: CHRONIC PAIN AFTER INGUINAL HERNIOTOMY
    Disease: Version SOC Term Classification Code Term Level
    14.1 10018065 - General disorders and administration site conditions 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-000751-25 Sponsor Protocol Number: AXS02II201501 Start Date*: 2016-05-02
    Sponsor Name:Jaro Karppinen
    Full Title: ZOLEDRONIC ACID, A LONG-ACTING BISPHOSPHONATE, FOR CHRONIC LOW BACK PAIN DUE TO MODIC CHANGES: A RANDOMIZED CONTROLLED TRIAL
    Medical condition: Chronic low back pain
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004859 10024891 Low back pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002671-27 Sponsor Protocol Number: 28.04.2008 Start Date*: 2008-07-14
    Sponsor Name:Department of Medical Gastroenterology
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL GROUP CLINICAL AND EXPERIMENTAL PILOTSTUDY OF PREGABALIN IN PATIENTS WITH CHRONIC PANCREATITIS
    Medical condition: Chronic pancreatitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033649 Pancreatitis chronic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004517-24 Sponsor Protocol Number: Remi-Pain-01 Start Date*: 2016-05-17
    Sponsor Name:Wilhelminen hospital
    Full Title: A prospective, open-label, proof-of-concept pilot study of the effects of a single one-hour target-controlled remifentanil infusion on pain in 24 patients with persistent postsurgical pain.
    Medical condition: Persistent postsurgical pain/Chronic postoperative pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012928-89 Sponsor Protocol Number: 1.1042009 Start Date*: 2009-10-21
    Sponsor Name:South Tees NHS Trust
    Full Title: Intrathecal injection of a single dose of Ziconotide (Prialt®) to evaluate the option of continuous administration via implanted pump. A Pilot Study
    Medical condition: Severe, Chronic pain in patients who require intrathecal analgesia
    Disease: Version SOC Term Classification Code Term Level
    101 10049475 Chronic pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004393-28 Sponsor Protocol Number: 06-2011 Start Date*: 2012-07-12
    Sponsor Name:Charité - Universitätsmedizin Berlin
    Full Title: "Effectiveness of leech therapy in treatment of chronic low back pain - a randomised controlled clinical study"
    Medical condition: chronic low back pain -diagnosis assured by specialist (orthopedy, neurology, pain therapy) as chronic low back pain for at least 3 month caused by nonspecific lumbar syndrome - averaged pain int...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-000058-73 Sponsor Protocol Number: LIPS Start Date*: 2012-09-14
    Sponsor Name:University of Liverpool [...]
    1. University of Liverpool
    2. Walton Centre NHS Foundation Trust
    Full Title: A multi-centre (UK) double-blind randomised parallel group placebo controlled trial to evaluate the efficacy, safety, and tolerability of Intravenous Immunoglobulin (IVIg) 0.5g/kg plus standard tre...
    Medical condition: Complex Regional Pain Syndrome
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-020087-38 Sponsor Protocol Number: 2.8022010 Start Date*: 2010-11-25
    Sponsor Name:South Tees Hospitals NHS Foundation Trust
    Full Title: Comparison of the Effects of Intermittent Boluses to Simple Continuous Infusion on Patient Global Perceived Effect in Intrathecal Therapy for Pain.
    Medical condition: Severe, chronic pain in patients who require intrathecal analgesia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10049475 Chronic Pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2004-001390-26 Sponsor Protocol Number: PRO-RENAL-REG-064 Start Date*: 2004-11-09
    Sponsor Name:Baxter R&D Europe SCRL
    Full Title: A Subjective Evaluation of Inflow Pain: Comparison of Extraneal to Extraneal Physiological pH
    Medical condition: Patients with End Stage Renal Disease (ESRD) undergoing peritoneal dialysis (PD) therapy and experiencing pain on infusion with Extraneal not related to the catheter or volume of dialysis fluid.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10014646 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed) DK (Completed) DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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